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brouillon SYMPA

The unique properties of light have long inspired its use in biology and medicine — to explore living systems, remotely influence biological processes, or treat various diseases. To this end, the different pathways by which absorbed light energy is converted within a photoactive system — such as fluorescence emission, heat or acoustic wave generation, and photoinduced molecular reactions — can be harnessed, offering a wide range of opportunities for diagnostic and therapeutic applications. By tuning molecular design and supramolecular assembly, these processes can be finely optimized and/or effectively combined to develop innovative and high-performance systems.

In this context, the team Synthèse d’Architectures Moléculaires Photo-Actives (SAMPA) focuses on the design, synthesis, and multiscale study of systems incorporating light-responsive motifs, aimed at developing innovative approaches in health-related research. The team’s activities are broad, from the design of small photoactive molecules to the construction of supramolecular and self-assembled architectures using macrocycles and macromolecules, with the goal of optimizing the optical properties of these systems or imparting additional functionalities relevant to the intended applications.

The team’s research is organized around three main thematic areas, which include the synthesis and characterization of: